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AbbVie Announces Positive Topline Results from Second Phase 3 UP-AA Trial Evaluating Upadacitinib (RINVOQÂź) for Alopecia Areata

In the second replicate study (Study 1) of the pivotal Phase 3 UP-AA clinical program, upadacitinib (RINVOQÂź) achieved the primary endpoint, demonstrating that 45.2% and 55.0% of patients with seve...

What are the projected market size and revenue opportunity for upadacitinib in alopecia areata, and how will pricing, reimbursement, and off‑label use influence AbbVie's long‑term earnings outlook? What is the expected timeline for FDA submission and potential approval for the alopecia areata indication, and how might that compare to competitors' pipelines? How will the positive Phase 3 results for upadacitinib in alopecia areata affect AbbVie's short‑term stock momentum and price target?
Symbol: ABBV
Clinical trials
21 days ago
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Sempra and ConocoPhillips Extend Partnership with Offtake Agreement for Port Arthur LNG Phase 2

SAN DIEGO, Aug. 21, 2025 /PRNewswire/ -- Sempra (NYSE: SRE) today announced that its subsidiary, Sempra Infrastructure, and ConocoPhillips (NYSE: COP) have signed a definitive 20-year sale and purc...

How might the extended partnership influence regional LNG price differentials and the market positioning of U.S. LNG supply in Asia and Europe? What impact will this long‑term contract have on Sempra's LNG project financing terms and the valuation of its Port Arthur Phase 2 assets relative to peers? How will the 20‑year, 4 Mtpa LNG offtake agreement affect Sempra's and ConocoPhillips' cash flow and earnings forecasts?
Symbol: SRE
Energy
21 days ago
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Blink and Presto Announce Strategic Collaboration to Provide Advanced Tools for EV Fleet Charging

New Collaboration Delivers a Streamlined Approach for EV Fleet and Rideshare Drivers to Charge on the Blink Network Through the Presto App Nationwide.

How does this strategic alliance position Blink relative to its competitors (e.g., ChargePoint, EVgo) in capturing the EV fleet and rideshare market share? What are the financial terms of the collaboration, including any cost sharing, revenue splits, or impact on Blink's profitability and cash flow? How will the Blink‑Presto partnership translate into incremental revenue and charging session volume for Blink?
Symbol: BLNK
Partnership
21 days ago
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ADAR1 Sends Open Letter to Keros Board of Directors Urging the Board to Engage Constructively on Strategy, Capital Allocation and Board Refreshment

AUSTIN, Texas, Aug. 21, 2025 /PRNewswire/ -- ADAR1 Capital Management, LLC (together with its affiliates, "ADAR1" or "we"), the largest stockholder of Keros Therapeutics (Nasdaq: KROS) ("Keros" or ...

How might the market view ADAR1's 13.3% stake and activism in terms of future dilution or financing needs? What potential board refreshment actions could alter Keros' governance structure and affect its long‑term growth prospects? How will ADAR1's push for strategic and capital allocation changes influence Keros' short‑term stock price?
Symbol: KROS
Governance
21 days ago
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