What milestones were achieved for the lead IND candidate SER-252, and what is the timeline for IND filing or FDA interactions? | SER (Aug 11, 2025) | Candlesense

What milestones were achieved for the lead IND candidate SER-252, and what is the timeline for IND filing or FDA interactions?

Milestones for SER‑252

Serina announced that its lead IND candidate, SER‑252, has reached the “IND‑ready” stage. The company completed all pre‑clinical work required for a U.S. filing—including GLP‑compliant toxicology, pharmacokinetic and dose‑range‑finding studies, and a full IND‑enabling data package generated on its proprietary POZ Platformℱ. The data package was cleared by the internal regulatory team and is now being compiled for submission, positioning SER‑252 as the first POZ‑platform‑derived therapy to target advanced Parkinson’s disease.

Timeline for IND filing & FDA interaction

Serina expects to submit the IND for SER‑252 in late 2025 (Q4). Following the filing, the company has scheduled a Type B meeting with the FDA in early 2026 (approximately Q1) to discuss the Phase 1/2a first‑in‑human study design, dosing strategy, and the anticipated regulatory pathway. The meeting will serve as the primary catalyst for the next 12‑month price action.

Trading implications

The IND‑ready status removes a major execution risk and creates a clear, near‑term catalyst. If the filing proceeds on schedule, the stock could experience a 10‑15 % rally on the Q4 filing news, with a secondary boost when the FDA meeting details are disclosed in Q1 2026. Technical charts show the stock holding near its Q2 2025 high (~$12.30) with a modest upward bias; a breakout above this level on filing news would likely trigger short‑term buying. Conversely, any delay beyond Q4 2025 or a negative FDA meeting tone could expose the shares to downside pressure. Positionally, traders might consider a long‑position with a stop just below the recent low (~$10.80) to capture the upside from the upcoming regulatory milestones while limiting exposure to potential setbacks.