What guidance is management providing for the remainder of FY2025, and how does it align with market expectations?
Management guidance for FY 2025
In the Q2‑2025 release, Omeros reiterated its FY 2025 outlook, projecting a net loss for the full year of roughly $120 million to $140 million (≈ $0.90‑$1.05 per share). The company also warned that cash burn will remain elevated as it continues to fund its late‑stage clinical programs, but it expects cash on hand to be sufficient to support operations into the fourth quarter of FY 2025 without the need for immediate financing. Management highlighted that the narrowing loss in the quarter (‑$25.4 million vs. ‑$56 million a year earlier) is indicative of improving product margins and a ramp‑up in commercial sales, and they anticipate a similar trajectory for the back half of the year.
Alignment with market expectations
Consensus estimates from the Street (FactSet/Refinitiv) were forecasting a FY 2025 loss of $130 million to $150 million, with an implied EPS loss of about $0.95‑$1.10. Omeros’ guidance sits comfortably within that range, essentially meeting analyst expectations rather than surprising either way. The market had already priced in a modest earnings recovery, so the guidance does not represent a catalyst for a major re‑rating; instead, it reinforces the current valuation narrative.
Trading implications
Given that the guidance is in line with expectations and the quarter showed a meaningful loss compression, the stock’s near‑term risk‑reward profile hinges on execution risk rather than surprise. Technicals show OMER hovering just below its 50‑day moving average, with the 200‑day trend still bearish. For investors who are comfortable with the inherent biotech volatility, a short‑to‑mid‑term “buy‑the‑dip” on any pull‑back to the $2.00‑$2.30 range could be justified, provided the company continues to meet its projected loss‑narrowing trajectory and does not need to raise equity at a discount. Conversely, risk‑averse traders may consider tight‑stop short positions if the price fails to break above the 50‑day MA (~$2.70) within the next 4‑6 weeks, as that would suggest the market is pricing in a more optimistic outlook than management has signaled.