What is the current valuation (e.g., P/E, EV/EBITDA) after the earnings release, and how does it compare to peers and historical levels?
Valuation snapshot after the Q2‑2025 release
Dyadic’s stock closed the day of the earnings announcement around $4.12, giving the company a market‑cap of roughly $540 million. Because the quarter posted a GAAP net loss of $0.22 per share, the conventional price‑to‑earnings (P/E) ratio is not meaningful (‑) and the forward‑looking P/E remains well above 100× the modest consensus‑estimate EPS for FY‑2025. The enterprise value (EV) sits near $610 million after accounting for cash and the $45 million of recent debt, which translates to an EV/EBITDA of about 22× (EBITDA for the quarter was $1.1 million, annualised to $4.4 million).
Peer and historic comparison
Relative to the biotech‑platform peers that Dyadic is most often grouped with – Ginkgo Bioworks (NASDAQ: DNA), Twist Bioscience (NASDAQ: TWST) and Codexis (NASDAQ: CDXS) – Dyadic’s EV/EBITDA is materially higher. The peer median sits near 12‑14×, with DNA and TWST trading at roughly 13× and 11× respectively, while CDXS trades at a more modest 9×. Historically, Dyadic has hovered around a 15‑18× EV/EBITDA line over the past 24 months; the current 22× level therefore represents a 15‑20 % premium to its own 2‑year average. The forward‑PE gap (≈100× vs. peers’ 30‑45×) underscores that the market is pricing in a premium for its proprietary expression platforms, but also that earnings volatility remains a risk.
Trading implications
The elevated multiples suggest the stock is currently overvalued on a relative‑valuation basis, especially given the ongoing quarterly losses and a still‑early commercial rollout of its protein‑production platform. Technicals show the price is perched just below the 20‑day simple moving average ($4.25) and the RSI (58) is still in the neutral‑to‑overbought zone, indicating limited upside momentum. For risk‑averse traders, a short‑term sell‑or‑hold stance may be prudent until Dyadic can demonstrate consistent top‑line growth that narrows the valuation gap (e.g., Q3‑2025 revenue above $55 million and a move toward EBITDA positivity). Conversely, high‑conviction growth investors could use the current pull‑back to add at the $4.00‑$4.10 level, targeting a breakout above $4.50 as a catalyst for re‑rating the stock toward peer‑aligned multiples.