ALNY News

New Post Hoc Analysis from the HELIOS-B Phase 3 Study Shows Vutrisiran Improved Measures of Heart Structure and Function in Patients with ATTR-CM

ALNY

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced results from new post hoc analyses of the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), an RNAi therapeutic approved for the treatment of the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) and the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR-PN) in adults. Data from cardiovascular magnetic re

November 8, 2025
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Alnylam Announces Pricing of Upsized Offering of $575 Million Convertible Senior Notes

ALNY

(NASDAQ:ALNY) CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (“Alnylam”) (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today the pricing of its previously announced private offering of $575 million aggregate principal amount of 0.00% convertible senior notes due 2028 (the “notes”) to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the “Securities Act”). The size of the offering was increa

September 10, 2025Debt Offering
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Alnylam Announces Proposed Offering of $500 Million Convertible Senior Notes

ALNY

(NASDAQ:ALNY) CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (“Alnylam”) (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it has commenced a private offering of $500 million aggregate principal amount of convertible senior notes due 2028 (the “notes”) to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the “Securities Act”). In connection with this offering, Alnylam expects to gran

New Data From Landmark HELIOS-B Phase 3 Study Presented at ESC Congress 2025 Demonstrate Vutrisiran’s Long-Term Cardiovascular Benefit in ATTR-CM

ALNY

(NASDAQ:ALNY) CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced results of new analyses from the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), an RNAi therapeutic approved for the treatment of the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) in adults. Data from the 12-month follow-up of the ongoing open-label extension (OLE) period of HELIOS-B were presented during an oral sess

Genentech and Alnylam Advance Zilebesiran Into Global Phase III Cardiovascular Outcomes Trial for People With Uncontrolled Hypertension

ALNY

(NASDAQ:ALNY) SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY) and Alnylam (Nasdaq: ALNY) today announced the decision to initiate a Phase III cardiovascular outcomes trial (CVOT) to evaluate the ability of zilebesiran, an RNAi therapeutic, to reduce the risk of major adverse cardiovascular events in patients with uncontrolled hypertension. This decision was informed by the comprehensive KARDIA Phase II program, including KARDIA-1, KARDIA-2 and

Alnylam to Advance Zilebesiran into Global Phase 3 Cardiovascular Outcomes Trial

ALNY

(NASDAQ:ALNY) CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced plans to initiate a Phase 3 cardiovascular outcomes trial (CVOT) to evaluate the potential of zilebesiran to reduce the risk of major adverse cardiovascular events. This decision is informed by results from the comprehensive KARDIA Phase 2 program, including KARDIA-3 results presented today as a late-breaking abstract at the European Society of Cardiology (ESC)

Alnylam to Webcast Presentations at Upcoming September Investor Conferences

ALNY

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present company overviews at the following upcoming investor conferences: Citi's 2025 Biopharma Back to School Conference on Wednesday, September 3, 2025 at 1:45 pm ET in Boston Morgan Stanley 23rd Annual Global Healthcare Conference on Monday, September 8, 2025 at 1:05 pm ET in New York City Bernstein Insights: Healthcare Leaders and Disru

Alnylam to Present Progress in Transforming the Treatment of Cardiovascular Disease with RNAi Therapeutics at European Society of Cardiology Congress 2025

ALNY

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced that the Company will present new data from its hypertension and transthyretin amyloidosis (ATTR) programs at the upcoming European Society of Cardiology (ESC) Congress 2025, taking place in Madrid, Spain, from August 29 - September 1, 2025. These presentations will highlight the potential of RNAi therapeutics to transform the treatment of cardiovascular diseas

Alnylam to Webcast Presentation at Canaccord Genuity 45th Annual Growth Conference

ALNY

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present a company overview at the Canaccord Genuity 45th Annual Growth Conference, on Tuesday, August 12, 2025 at 8:00 am ET. A live audio webcast of the presentation will be available on the Investors section of the Company’s website, www.alnylam.com/events. A replay will be available on the Alnylam website within 48 hours after the event.

Alnylam Announces Promotion of Pushkal Garg to Chief Research and Development Officer

ALNY

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNA interference (RNAi) therapeutics company, today announced that Pushkal Garg, M.D., has been appointed Executive Vice President, Chief Research and Development Officer to oversee an integrated R&D organization. Building on the launch of AMVUTTRA® in transthyretin amyloidosis with cardiomyopathy (ATTR-CM), Alnylam is entering a new phase of growth, and a combined R&D organization will accelera

What 18 Analyst Ratings Have To Say About Alnylam Pharmaceuticals

ALNY

June 12, 2025
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JP Morgan Maintains Overweight on Alnylam Pharmaceuticals, Raises Price Target to $338

ALNY

June 12, 2025
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The European Commission Approves Alnylam Pharmaceuticals' Orphan RNAi Therapeutic Amvuttra (Vutrisiran) For Wild-type Or Hereditary Transthyretin Amyloidosis In Adult Patients With Cardiomyopathy As An Additional Indication

ALNY

June 9, 2025
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Moderna Beats Alnylam Appeal In COVID Vaccine Patent Case

ALNY

The Federal Circuit upheld a ruling that Moderna's COVID-19 vaccine does not infringe Alnylam's mRNA patents related to the SM-102 lipid used in Spikevax.

June 5, 2025
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Here's How Much $1000 Invested In Alnylam Pharmaceuticals 20 Years Ago Would Be Worth Today

ALNY

May 26, 2025
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Reported Saturday, Alnylam's Vutrisiran Reduces All-Cause And Cardiovascular Mortality By Over 30% In ATTR-CM Patients, New 42-Month HELIOS-B Data Show

ALNY

May 19, 2025
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Alnylam Pharma To Present Latest Data From Flagship Transthyretin Amyloidosis Franchise At Upcoming Heart Failure 2025 Congress

ALNY

May 12, 2025
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$100 Invested In Alnylam Pharmaceuticals 15 Years Ago Would Be Worth This Much Today

ALNY

May 8, 2025
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UBS Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $349

ALNY

May 2, 2025
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Alnylam Delivers Q1 Surprise, Analysts Highlight Amvuttra Momentum, Limited Tariff Risk

ALNY

Alnylam analysts highlight Amvuttra's strong launch positioning and limited tariff risk, with bullish ratings maintained despite early launch volatility.

May 2, 2025
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Chardan Capital Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $325

ALNY

May 2, 2025
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$100 Invested In Alnylam Pharmaceuticals 20 Years Ago Would Be Worth This Much Today

ALNY

May 1, 2025
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Alnylam Pharmaceuticals Affirms FY2025 Sales Guidance of $2.70B-$3.00B vs $2.91B Est

ALNY

May 1, 2025
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Alnylam Pharmaceuticals Q1 Adj. EPS $(0.01) Beats $(1.03) Estimate, Sales $594.19M Beat $585.82M Estimate

ALNY

May 1, 2025
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Alnylam Receives Positive CHMP Opinion For Vutrisiran In Treatment Of ATTR Amyloidosis With Cardiomyopathy

ALNY

April 28, 2025
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How Do Investors Really Feel About Alnylam Pharmaceuticals?

ALNY

April 21, 2025
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Here's How Much You Would Have Made Owning Alnylam Pharmaceuticals Stock In The Last 15 Years

ALNY

April 15, 2025
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Morgan Stanley Maintains Equal-Weight on Alnylam Pharmaceuticals, Lowers Price Target to $268

ALNY

April 11, 2025
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Needham Reiterates Buy on Alnylam Pharmaceuticals, Maintains $320 Price Target

ALNY

April 9, 2025
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Vertex, Alnylam Best Positioned As Biopharma Braces For Tariff Impact, Goldman Sachs Flags Regeneron, Biogen Risks

ALNY

Trump's new tariff move may raise U.S. pharma costs, with analysts warning of risks tied to EU manufacturing and shifting healthcare policies.

April 4, 2025
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Is Alnylam Pharmaceuticals Gaining or Losing Market Support?

ALNY

April 4, 2025
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HC Wainwright & Co. Reiterates Buy on Alnylam Pharmaceuticals, Maintains $500 Price Target

ALNY

April 2, 2025
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Scotiabank Maintains Sector Outperform on Alnylam Pharmaceuticals, Raises Price Target to $342

ALNY

March 31, 2025
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If You Invested $100 In This Stock 20 Years Ago, You Would Have This Much Today

ALNY

March 31, 2025
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Redburn Atlantic Initiates Coverage On Alnylam Pharmaceuticals with Buy Rating, Announces Price Target of $353

ALNY

March 31, 2025
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FDA Approves Sanofi's Hemophilia Drug

ALNY

FDA approves Sanofi's Qfitlia, the first antithrombin-lowering therapy for hemophilia A or B, reducing bleeding episodes with as few as six injections per year.

March 31, 2025
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Stifel Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $345

ALNY

March 31, 2025
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Reported Saturday, Alnylam Presents HELIOS-B Data Highlighting Vutrisiran's Multidimensional Benefits In ATTR-CM At Annual Scientific Session 2025

ALNY

March 31, 2025
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Sanofi Says With Qfitlia Approval, FDA Also Cleared Siemens Healthineers' Innovance Antithrombin Assay As Companion Diagnostic For Qfitlia

ALNY

March 28, 2025
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Alnylam Pharmaceuticals Presents 'Convincing Multi-Billion Dollar Opportunity': Analyst Upgrades Stock

ALNY

Alnylam's Amvuttra wins FDA approval for ATTR-CM, expanding its market reach. JP Morgan upgrades the stock, projecting strong sales and a multi-billion opportunity.

March 24, 2025
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Carnival To Rally Around 48%? Here Are 10 Top Analyst Forecasts For Monday

ALNY

March 24, 2025
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JP Morgan Upgrades Alnylam Pharmaceuticals to Overweight, Raises Price Target to $328

ALNY

March 24, 2025
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Robinhood, Roku And Shopify Are Among Top 10 Large-Cap Gainers Last Week (Mar 17-Mar 21): Are The Others In Your Portfolio?

ALNY

Best performing large-cap stocks last week: Alnylam Pharma up 16%, Roku up 14%, Elbit Systems up 13%, Venture Global up 12%, Boeing up 11%. Are they in your portfolio?

March 23, 2025
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Citigroup Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $351

ALNY

March 21, 2025
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Canaccord Genuity Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $390

ALNY

March 21, 2025
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RBC Capital Maintains Outperform on Alnylam Pharmaceuticals, Raises Price Target to $330

ALNY

March 21, 2025
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Scotiabank Maintains Sector Outperform on Alnylam Pharmaceuticals, Raises Price Target to $338

ALNY

March 21, 2025
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Alnylam's Amvuttra Secures FDA Approval For Expanded Use For Rare Heart Disease, Stock Jumps

ALNY

Alnylam's Amvuttra receives FDA approval for ATTR-CM, expanding its use and securing broad insurance coverage as global regulatory reviews continue.

March 21, 2025
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Wells Fargo Maintains Equal-Weight on Alnylam Pharmaceuticals, Raises Price Target to $287

ALNY

March 21, 2025
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B of A Securities Maintains Buy on Alnylam Pharmaceuticals, Raises Price Target to $325

ALNY

March 21, 2025
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