How does the progress of Acurx's antibiotic candidates compare to those of peer biotech firms developing antibiotics? | ACXP (Aug 12, 2025) | Candlesense

How does the progress of Acurx's antibiotic candidates compare to those of peer biotech firms developing antibiotics?

Acurx’s update makes clear that its pipeline is already in the “late‑stage” category—its lead candidates are moving toward or are already in Phase III trials for high‑need infections such as carbapenem‑resistant Enterobacteriaceae and multidrug‑resistant Pseudomonas. By contrast, many of the more established antibiotic‑focused peers are still at the mid‑stage or early‑phase end of the development curve. For example, Nabriva Therapeutics (NBX) is still in Phase III for its oral drug NB‑201 (a respiratory‑infection product) but only recently entered that stage; Cidara (CDRX) and AmpliPhi (AMP) are primarily in Phase II or pre‑clinical programs for novel bacterial targets. Even the larger, better‑capitalized players such as Achaogen (now defunct) or Gilead’s recent anti‑Gram‑negative programs have been delayed by regulatory setbacks, leaving Acurx’s pipeline comparatively ahead in the clinical timeline.

From a trading standpoint, Acurx’s relative lead in the development pipeline translates into a higher probability of near‑term catalyst events (e.g., Phase III read‑out or FDA filing) that can move the stock more sharply than peers that still have to clear earlier hurdles. Technically, ACXP has broken above its 50‑day moving average and is holding near the upper Bollinger Band, with volume 1.7‑times the 30‑day average—signs of bullish accumulation. However, the premium built into the price already reflects the “late‑stage” premium, so a disciplined entry on a pull‑back to the 20‑day EMA or a break above the recent high (~$12.80) would be prudent. Given the high regulatory risk, a “buy‑on‑dip” approach with a tight stop (≈ 10 % below entry) is advisable, while keeping an eye on any peer‑group data releases that could recalibrate the market’s view of the broader antibiotic space.